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    <loc>https://www.trpvpharma.com/new-page</loc>
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  <url>
    <loc>https://www.trpvpharma.com/about</loc>
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    <lastmod>2022-05-12</lastmod>
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      <image:title>About</image:title>
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  <url>
    <loc>https://www.trpvpharma.com/new-page-1</loc>
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    <lastmod>2022-06-17</lastmod>
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      <image:title>Science</image:title>
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  <url>
    <loc>https://www.trpvpharma.com/our-team</loc>
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    <lastmod>2022-07-06</lastmod>
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      <image:title>Our Team - Fred Sexton - CEO</image:title>
      <image:caption>Tobias Keene, D.D.S. Hailing from Richmond, Virginia, Dr. Tobias Keene brings a bit of unabashed Southern hospitality to all his patients. He moved to Washington, D.C. over thirty years ago as a freshman at Ivy College. Right after graduation, he attended World University’s School of Dentistry. Before opening Keene Dental in 1994, he worked for free clinics and some of the finest practices in the District. He is part of the 123 Dental Association and stays up-to-date on the latest dental discoveries. When not striving to keep his patients happy and healthy, he’s enjoys hiking with his family in Rock Creek Park.</image:caption>
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      <image:title>Our Team - Jack Rubinstein, MD - CMO</image:title>
      <image:caption>Jack is an Associate Professor of Medicine at the University of Cincinnati (UC) and the Associate Director of Cardiology at the Cincinnati VAMC. He is an NIH/AHA/VA funded researcher with over a decade of experience in translational cardiovascular research with a specific focus on TRP channel modulation of cardiac function. Further, Dr. Rubinstein is the director of the Physician Scientist Training Program at UC where he focuses on mentoring the next generation of physician scientists. Beyond his clinical and scientific pursuits Jack is an author and horse enthusiast.</image:caption>
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  <url>
    <loc>https://www.trpvpharma.com/our-team-1</loc>
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    <lastmod>2023-02-23</lastmod>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/62770912daf958266fb25deb/83007d23-5234-4d0d-a650-c4d813d598e0/Litsa+Kranias+Photo+cropped.jpg</image:loc>
      <image:title>Key Advisors - Evangelia Kranias, PhD - Calcium Channel &amp; Diagnostic Marker Advisor</image:title>
      <image:caption>Dr Kranias is the Hanna Professor, Distinguished University Research Professor, Director of Cardiovascular Biology and Professor of Pharmacology and Systems Physiology at the University of Cincinnati College of Medicine. Research studies in the Kranias lab over the past four decades have focused on the role of Ca2+-handling and Ca2+-signaling in the regulation of myocardial function and survival in health and disease. In particular, Dr Kranias has focused on unraveling the mechanisms underlying the impaired regulation of sarcoplasmic reticulum Ca2+-cycling in cardiac and skeletal myopathies to identify novel therapeutic targets. She has used an integrative approach with state-of-the-art techniques, spanning the molecular, biomedical, cellular, intact organ and intact animal levels. Importantly, she has generated and characterized a large number of genetically altered mouse models, affording significant insights into the regulation of cardiac function, apoptosis, necrosis and autophagy. The Kranias laboratory studies have been extended from the bench to the clinic, including the identification of human variants in key Ca-cycling genes that may serve as potential prognostic or diagnostic markers for the development of arrhythmia and heart failure. Her pioneering research findings have been published in top tier journals and her projects were funded from NIH for almost four decades. Dr. Kranias has organized, chaired and spoke at numerous National and International meetings. She has also been a dedicated mentor of over 70 Ph.D. students and post-doctoral fellows. She has received many National and International awards and honors, including the AHA Distinguished Scientist Prize, the 2019 AHA Basic Research Prize, the George E. Brown Memorial Lecture, the International Society of Heart Research Peter Harris Award Lecture and the President’s Award Lecture, and was elected as a corresponding member of the Athens Academy. Dr. Kranias has also served on the Councils of the Biophysical Society and the ISHR (International and NA), the AHA Research Committee, and as Associate Editor or Editorial Board member of several journals as well as reviewer on numerous panels and committees.</image:caption>
    </image:image>
    <image:image>
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      <image:title>Key Advisors - Moheb Nasr, PhD - Regulatory Advisor</image:title>
      <image:caption>Moheb Nasr, PhD - Regulatory Advisor</image:caption>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/62770912daf958266fb25deb/5aef7c7a-d4bb-41e4-8fa3-2418b621f6be/RA+image.jpg</image:loc>
      <image:title>Key Advisors - Roman Ajzen, JD - Financial Advisor</image:title>
      <image:caption>Roman Ajzen, JD - Financial Advisor</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/62770912daf958266fb25deb/80770af3-5519-418e-bae0-ca4751070203/molkentin1+small+image+250+h.jpg</image:loc>
      <image:title>Key Advisors - Jeffery Molekentin, PhD - Drug Target Modeling Advisor</image:title>
      <image:caption>Jeff Molekentin, PhD - Drug Target Modeling Advisor</image:caption>
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    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/62770912daf958266fb25deb/3cd32da7-c305-4ec1-b0ae-cad662422db1/Givertz+Headshot+250+h.jpg</image:loc>
      <image:title>Key Advisors - Michael Givertz, MD - Cardiology Advisor</image:title>
      <image:caption>Dr. Michael M. Givertz is the Medical Director of Heart Transplant and Mechanical Circulatory Support Program and a heart failure/transplant specialist at Brigham and Women’s Hospital (BWH). He is also past chair of the New England Consortium of Heart Transplant and Professor of Medicine at Harvard Medical School (HMS). He received his medical degree from HMS. He then completed an internal medicine residency program at BWH and a chief residency program in internal medicine at the Veterans Affairs Medical Center in West Roxbury (now VA Boston Healthcare System). He completed two fellowships at BWH: one in cardiovascular disease and the other in heart failure/transplant. He is board certified in cardiovascular disease, advanced heart failure and transplant cardiology. Dr. Givertz’s clinical interests include heart transplant, mechanical circulatory support, peripartum cardiomyopathy, heart failure and secondary pulmonary hypertension. His research focuses on cardiorenal interactions in acute heart failure and novel tools to assess cardiac function and guide therapy. He has authored over 150 peer-reviewed publications and received research funding from the National Institutes of Health.</image:caption>
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  <url>
    <loc>https://www.trpvpharma.com/contact</loc>
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    <lastmod>2022-06-17</lastmod>
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      <image:title>Contact</image:title>
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  <url>
    <loc>https://www.trpvpharma.com/press</loc>
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    <lastmod>2023-02-23</lastmod>
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      <image:title>Press &amp; Related Science</image:title>
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